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bp0003rdr14 | Development of the Reproductive Axis | REDR1994

Inhibin and activin in embryonic and fetal development in ruminants

Jenkin G , McFarlane J , de Kretser DM

Inhibin, activin and follistatin are protein hormones with diverse physiological roles. The involvement of inhibin in the regulation of pituitary FSH production and secretion in adult males and non-pregnant females is well established. However, it is unlikely that inhibin plays a similar role in pregnancy in ruminants. Inhibin and activin molecules show a high degree of structural similarity to potent growth and differentiation factors of the transforming growth factor β ...